Plain-English translation of NCT04508790 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a combination of three medications—, , and —to see if they can help people with multiple myeloma that has come back or stopped responding to previous treatments. Multiple myeloma is a cancer of blood cells, and this research aims to find out whether this medication combination can slow or stop the cancer's growth. Researchers will track how many patients improve, how long the improvement lasts, and what side effects occur.
Multiple myeloma can return or become resistant to standard treatments, leaving patients with limited options. This trial exists to test whether this new medication combination might help people whose cancer no longer responds to earlier therapies.
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You would take three oral medications by mouth on a rotating schedule over a 28-day cycle: every day, for 21 days, and on specific days. This cycle repeats as long as the treatment is working and side effects are manageable. You'll have regular appointments at City of Hope Medical Center for blood tests and check-ups, with a follow-up visit 30 days after treatment ends, then every 3 months thereafter to monitor your progress and any side effects.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States