Plain-English translation of NCT04516447 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new medication called in combination with either standard chemotherapy drugs or a targeted therapy called . The study wants to understand whether the medication is safe, how well it works, and what the right dose should be for people with advanced ovarian, peritoneal, or fallopian tube cancer.
Current treatments for ovarian cancer work for some patients, but many eventually stop responding, especially to platinum-based chemotherapy. This medication is designed to work alongside these standard treatments to potentially help more patients and extend how long the cancer stays controlled.
You likely qualify if…
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You would receive the new medication by mouth, combined with either intravenous chemotherapy or infusions given at regular intervals. You would attend clinic visits for treatment administration, blood tests, and scans to monitor how your cancer responds. The study involves two main parts testing different drug combinations, and depending on which arm you join, you may receive treatment over several months while your doctors carefully track your response and any side effects.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
United States