Plain-English translation of NCT04521699 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a handheld device called CalmiGo can help people who have recently had a heart attack recover better by managing stress during their rehabilitation. The device works like an inhaler and is used once daily for 12 weeks. Researchers will measure how this treatment affects heart health markers, stress levels, and overall cardiovascular risk compared to standard cardiac rehabilitation alone.
After a heart attack, stress and anxiety can negatively affect heart health and recovery. This study exists to see if adding a simple, non-medication stress management tool to standard cardiac rehabilitation can help patients heal better and reduce their risk of future heart problems.
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If you enroll, you will first complete baseline testing including blood work, heart health assessments, and stress tests. You will then be randomly assigned to either use the CalmiGo device once daily for 12 weeks during your cardiac rehabilitation, or to continue with standard cardiac rehabilitation alone. After 12 weeks, you will return for repeat testing to see if the device helped improve your heart health and stress levels compared to the starting point.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Collaborators
CalmiGO
Enrollment target
~100 participants
Started
January 2022
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anna Pick
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.