Plain-English translation of NCT04531696 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
UPTIDER is a research program that asks people with advanced breast cancer or inherited cancer syndromes to donate tissue samples after death. Researchers will study these samples in detail to understand how breast cancer spreads, why it sometimes resists treatment, and how inherited cancer genes affect tumor biology.
Researchers need access to real tumor tissue to understand why some breast cancers become resistant to treatment and how inherited cancer genes contribute to disease. This knowledge could lead to better treatments and earlier detection for future patients.
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If you enroll, you continue your regular medical care—there are no special visits or medications required during your lifetime. You simply agree that after death, researchers will collect tissue samples from various parts of your tumor and body for detailed analysis. The tissue donation happens only once, after passing, and involves no impact on your medical treatment or comfort during life.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
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