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Oral Metformin for Treatment of ABCA4 Retinopathy — Stella

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Oral Metformin for Treatment of ABCA4 Retinopathy

Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.

Trial locations(2 sites)

United States

National Institutes of Health Clinical Center, Bethesda, Maryland

University of Michigan, Ann Arbor, Michigan

Key details

Phase

Early testing / Safety & dosing

Sponsor

National Eye Institute (NEI)

Enrollment target

~56 participants

Started

November 2020

Primary completion

September 2028

Age range

12 Years – 100 Years

Last updated October 2025

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