Plain-English translation of NCT04547595 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial examined whether hypnosis could help patients feel less pain and anxiety during a knee joint-cleaning procedure called lavage, which is used to treat painful knee osteoarthritis. Some patients received standard pain management alone, while others received standard care combined with a hypnosis intervention during the procedure. The researchers wanted to see if adding hypnosis would reduce pain levels and how much pain medication patients needed after the procedure.
Joint lavage can cause significant pain and anxiety in patients with knee osteoarthritis, which typically requires strong pain and anti-anxiety medications. This trial was designed to explore whether the new treatment of hypnosis could help manage these symptoms more effectively and potentially reduce the need for medications.
Patients were randomly assigned to either receive standard care during their knee lavage procedure, or standard care combined with a hypnosis intervention. Researchers followed participants for one week after the procedure to measure their pain levels and track how much pain medication they used. The entire study took place over two years, with enrollment lasting about 18 months.
AI-generated summary from trial data · Jul 12, 2026 · Not medical advice
France
Sponsor
Assistance Publique - Hôpitaux de Paris
Collaborators
URC-CIC Paris Descartes Necker Cochin
Enrollment target
~100 participants
Started
October 2021
Primary completion
January 2025
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.