Plain-English translation of NCT04550728 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
After a stroke, many people struggle to regain full control of their legs and walking. This trial is testing a hybrid rehabilitation system that combines two technologies: a robot that guides gentle stretching and movement of the ankle, and functional electrical stimulation (FES), which uses mild electrical pulses to activate muscles that may not be responding well on their own. Researchers want to see if using these tools together at home can help stroke survivors improve their strength, reduce stiffness, and walk better than using the robot alone.
Many stroke survivors have weakness or difficulty controlling their legs because the signals from their brain to their muscles are disrupted. While the robot can guide movement and FES can activate dormant muscles, researchers believe combining both technologies may be more effective than either one alone—and doing this training at home could make it more convenient and accessible for patients.
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You will be randomly assigned to receive either ankle robot training alone or ankle robot training combined with electrical stimulation. Most of your training will happen at home with your caregiver's assistance, though you may have some initial assessment visits at the clinic. The study aims to enroll 60 participants and will evaluate how well these treatments help improve your leg strength, reduce stiffness, and improve your ability to walk.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United States