Plain-English translation of NCT04556188 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying heart surgery for people with rheumatic heart disease at a hospital in Ethiopia. Researchers want to see how well patients recover after surgery over six months, and how well blood thinners work for patients who receive mechanical heart valves. They'll compare results between Ethiopian patients who had surgery, Ethiopian patients still waiting for surgery, and Norwegian patients who have had similar procedures.
Rheumatic heart disease is a serious condition that damages heart valves, and many people in Ethiopia need surgery but don't have access to it. This study will help doctors understand whether developing a surgical program in Ethiopia can save lives and improve outcomes, and whether patients there can safely manage blood-thinning medications after valve replacement.
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If you are selected for surgery, you will receive heart valve surgery at the hospital as part of the study. You will then be followed up for six months with visits to check how you are healing, including heart exams and blood tests. Researchers will track your recovery, any complications, and how well your new valve is working. Some participants will also be monitored for a longer period if they need blood-thinning medications.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Ethiopia
Norway