Plain-English translation of NCT04575935 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
The LANCE trial is testing whether minimally invasive surgery (using small incisions and cameras) works as well as traditional open surgery for removing cancer after in women with advanced ovarian, fallopian tube, or peritoneal cancer. Both groups will receive before and after surgery, but the trial is comparing which surgical approach gives patients better long-term outcomes and quality of life.
Doctors want to know if minimally invasive surgery—which causes less pain and faster recovery—can be just as effective as traditional open surgery for these cancers. Current treatment uses larger incisions, but if smaller incisions work equally well, patients could experience less trauma to their bodies and recover faster.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to either minimally invasive surgery (using small incisions) or traditional open surgery, both performed within 6 weeks after your last session. After surgery, you'll receive additional within 6 weeks. Throughout the trial, you'll complete questionnaires about your quality of life, and your surgical outcomes—including any complications, recovery time, and long-term disease control—will be carefully tracked. The trial will follow you over time to see how well each approach works.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States