Plain-English translation of NCT04577599 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Lung Neoplasms research guide โThis study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing whether low-dose CT scans can safely detect lung cancer early in younger adults (ages 40-54) who have smoked heavily. Researchers want to understand how often lung cancer is found at each screening visit and whether these scans work well for people in this age group who may not normally qualify for standard lung cancer screening.
Most lung cancer screening programs focus on older adults, but many younger heavy smokers are not screened and may have cancer that goes undetected. This trial exists to understand whether starting screening earlier could catch lung cancers at a stage when they are easier to treat.
You likely qualify ifโฆ
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You would visit the mobile screening unit at locations in North or South Carolina for low-dose CT scans at three time points. The first scan happens at your initial visit, with two follow-up scans scheduled at later visits. Each CT scan takes only a few minutes and uses a very low dose of radiation. You would also answer questions about your health, smoking history, and background, which helps researchers understand screening results.
AI-generated summary from trial data ยท Aug 8, 2026 ยท Not medical advice
United States
Sponsor
Wake Forest University Health Sciences
Collaborators
Leon Levine Foundation
Enrollment target
~1,160 participants
Started
January 2021
Primary completion
October 2028
Age range
40 Years โ 54 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Darcy Doege, RN
LCI
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.