Plain-English translation of NCT04593498 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →This research study is looking at people who have frequent extra heartbeats detected on heart monitors (called supraventricular ectopic activity). Researchers want to understand whether these extra beats mean someone is more likely to develop atrial fibrillation — an irregular heart rhythm that can increase stroke risk. The study will compare people with these extra beats to similar people without them, tracking both groups over several years.
Doctors have noticed that people with frequent extra heartbeats seem to be at higher risk for atrial fibrillation and stroke, but they don't fully understand why or how to predict who will develop these problems. This study aims to find biological markers in the blood and heart changes that could help doctors identify which patients are most at risk.
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If you qualify, you would wear a portable heart monitor (Holter monitor) for 14 days at the start. You'll also have blood tests, an ultrasound of your heart, blood pressure monitoring, and an artery stiffness test. You'll return for similar tests again after about 21 months. Four years after your initial screening, researchers will contact you by phone or check your medical records to see what has happened with your heart health. The study involves about 250 people total — 125 with the extra heartbeats and 125 without them, for comparison.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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