Plain-English translation of NCT04595630 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
After coronary bypass surgery, sometimes the new grafts become blocked. This study is testing whether a blood test that measures cardiac troponin (a heart damage marker) can safely and accurately detect early graft blockages. Right now, doctors have to do invasive procedures to check for blockages, which carry risks. The researchers want to see if this blood test could be a safer alternative.
Currently, the only reliable way to confirm a blocked bypass graft is an invasive heart catheterization procedure, which can cause serious complications like bleeding or kidney damage. This trial exists to find a safer, non-invasive way to identify blocked grafts early so doctors can treat them quickly.
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After your bypass surgery, you would have blood tests done to measure heart damage markers (this is often routine after surgery anyway). Before you leave the hospital, you would also have a special heart CT scan to check if any grafts are blocked. Researchers will then compare the blood test results with the CT scan findings to see how well the blood test predicts graft blockage. The entire process happens around the time of your hospital stay for surgery.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Croatia
Poland
Switzerland
Sponsor
University Hospital, Basel, Switzerland
Enrollment target
~480 participants
Started
July 2021
Primary completion
December 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Denis Berdajs, Prof. Dr. med.
Department of Cardiac Surgery, University Hospital Basel
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.