Plain-English translation of NCT04600115 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This research study is testing new MRI imaging techniques designed specifically to understand heart failure with preserved ejection fraction (HFpEF) — a condition where your heart pumps normally but has trouble relaxing and filling with blood. Researchers want to use these advanced imaging methods to see blood flow patterns in the heart muscle that regular imaging might miss, which could help doctors predict which patients will respond to different treatments.
Many drug treatments for this type of heart failure have not worked well, and doctors don't fully understand what's causing the problem in each patient. This new imaging approach may help identify the specific changes happening in the heart muscle and blood vessels, which could lead to better, more personalized treatments in the future.
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You would come to the hospital or imaging center for at least one visit to undergo MRI scans of your heart. The MRI machine takes detailed pictures of your heart while you lie still inside the scanner. Some participants may receive medications like or to stress the heart during imaging, similar to a stress test, while others will have scans without stress agents — your doctor will determine which is right for you. The entire visit typically takes a few hours.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States