Plain-English translation of NCT04606095 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are testing whether a procedure called HD-tDCS (high-definition transcranial direct current stimulation)—a non-invasive way to stimulate specific areas of the brain—can help reduce fibromyalgia pain. The study will first compare brain activity patterns between people with fibromyalgia and healthy volunteers, then test whether this brain stimulation treatment can decrease pain and change abnormal brain activity patterns in fibromyalgia patients.
Fibromyalgia causes widespread pain, and researchers have noticed that people with this condition show unusual patterns of synchronized brain activity. This trial exists to test whether targeting and reducing this abnormal brain synchronization with stimulation could be a new way to treat fibromyalgia pain.
If you have fibromyalgia, you would first complete three study visits plus an observation period (up to 33 days total) where researchers measure your brain activity using EEG, test your pain sensitivity, and perform brain imaging (MRI). Then you would receive two weeks of daily brain stimulation treatment (or sham treatment) five days per week, with follow-up brain scans and surveys to see if the treatment changed your pain and brain activity. Healthy volunteers participate only in the first measurement phase with no treatment.
AI-generated summary from trial data · Oct 4, 2026 · Not medical advice
United States