Plain-English translation of NCT04612322 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study collecting medical information from about 1,000 patients who have chest pain (angina) caused by problems in the small blood vessels of the heart, rather than blockages in the larger arteries. Doctors will measure how well these small vessels are working and follow patients over 5 years to understand how the condition affects their health and daily life.
Many patients experience chest pain even though their major heart arteries appear normal on standard tests. This study exists to better understand what causes this small vessel disease, how it progresses, and what outcomes patients can expect—so doctors can develop better treatments and care plans.
You likely qualify if…
You likely don't qualify if…
You will undergo standard heart function tests (including measurements of how well your small blood vessels work) at a hospital. After that, you'll be followed up by phone at 12 months and again at 5 years to check on your health, symptoms, and quality of life. The study does not require you to change your regular medical care or take any new medications—researchers are simply observing and tracking your progress over time.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
Germany
Sponsor
Johannes Gutenberg University Mainz
Enrollment target
~1,000 participants
Started
October 2020
Primary completion
October 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 85 Years
Last updated on clinicaltrials.gov in March 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Tommaso Gori, Dott med, PhD
Johannes Gutenberg University Mainz
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.