Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 — Stella
Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
(764 sites) United States
Local Institution - 007-556-A, Goodyear, Arizona USOR - Arizona Oncology - Prescott Valley, Prescott Valley, Arizona Local Institution - 007-568-A, Safford, Arizona Local Institution - 007-568-B, Safford, Arizona Local Institution - 007-568-C, Safford, Arizona Local Institution - 007-568-D, Safford, Arizona Local Institution - 007-568-E, Safford, Arizona Arizona Clinical Research Center, Tucson, Arizona Highlands Oncology Group - Springdale, Springdale, Arkansas Providence - Saint Joseph Home Health - Anaheim, Anaheim, California The Oncology Institute of Hope and Innovation - Corporate Office, Cerritos, California Local Institution - 007-777, Fountain Valley, California Local Institution - 007-778, Laguna Hills, California Local Institution - 007-898-B, Long Beach, California MemorialCare - Long Beach Medical Center, Long Beach, California TRIO - Cancer & Blood Specialty Clinic - Los Alamitos, Los Alamitos, California Local Institution - 007-579, Los Angeles, California Local Institution - Unk045, Rancho Mirage, California San Francisco Veterans Affairs Medical Center, San Francisco, California UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California Local Institution - 007-898-C, Santa Ana, California Providence Medical Group - Santa Rosa, Santa Rosa, California Stockton Hematology Oncology Medical Group (SHOMG) - Stockton (Suite B), Stockton, California Local Institution - 007-898-A, Whittier, California Local Institution - 007-872-H, Aurora, Colorado Local Institution - 007-872-D, Boulder, Colorado Local Institution - 007-872-L, Centennial, Colorado Local Institution - 007-872-C, Colorado Springs, Colorado Local Institution - 007-872-K, Colorado Springs, Colorado Local Institution - 007-872-E, Denver, Colorado Local Institution - 007-872-I, Denver, Colorado Local Institution - 007-872-A, Lakewood, Colorado Local Institution - 007-872-J, Littleton, Colorado USOR - Rocky Mountain Cancer Centers - Lone Tree, Lone Tree, Colorado Local Institution - 007-872-G, Longmont, Colorado Local Institution - 007-872-B, Pueblo, Colorado Local Institution - 007-872-F, Thornton, Colorado Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut Local Institution - 007-5476, Washington D.C., District of Columbia GenesisCare USA, Aventura, Florida Bay Pines Veterans Affairs Healthcare System, Bay Pines, Florida Local Institution - 007-922-A, Bonita Springs, Florida Local Institution - 007-922-D, Bradenton, Florida Local Institution - 007-922-E, Cape Coral, Florida Local Institution - 007-896-A, Celebration, Florida Local Institution - 007-926-B, Daytona Beach, Florida Local Institution - 007-562-B, Fleming Island, Florida SCRI - Florida Cancer Specialists - South Region Research Office, Fort Myers, Florida Local Institution - 007-922-B, Fort Myers, Florida Local Institution - 007-922-C, Fort Myers, Florida 21st Century Oncology of Jacksonville - North Lee Street, Jacksonville, Florida Local Institution - 007-562-D, Jacksonville, Florida Local Institution - 007-562-E, Jacksonville, Florida Local Institution - 007-562-G, Jacksonville, Florida Local Institution - 007-829, Jacksonville, Florida Cancer Specialists of North Florida - Southpoint, Jacksonville, Florida Local Institution - 007-562-C, Jacksonville, Florida Local Institution - 007-562-F, Jacksonville Beach, Florida Miami Veterans Affairs Healthcare System, Miami, Florida Local Institution - 007-922-F, Naples, Florida Local Institution - 007-922-G, Naples, Florida AdventHealth Orlando, Orlando, Florida USOR - Woodlands Medical Specialists, Pensacola, Florida Local Institution - 007-922-H, Port Charlotte, Florida Local Institution - 007-562-A, Saint Augustine, Florida Local Institution - 007-922-I, Sarasota, Florida Local Institution - 007-922-J, Sarasota, Florida Local Institution - 007-926-D, Stuart, Florida Local Institution - 007-924-A, Tallahassee, Florida SCRI - Florida Cancer Specialists - Tallahassee Cancer Center, Tallahassee, Florida James A. Haley Veterans Hospital, Tampa, Florida Local Institution - Unk065, Tampa, Florida Local Institution - 007-922-L, Venice, Florida Local Institution - 007-922-K, Venice, Florida Local Institution - 007-926-C, Vero Beach, Florida Local Institution - 007-926-A, Wellington, Florida SCRI - Florida Cancer Specialists - West Palm Beach, West Palm Beach, Florida Local Institution - Unk072, Weston, Florida University Cancer & Blood Center (UCBC) - Athens, Athens, Georgia Local Institution - Unk052, Atlanta, Georgia Local Institution - 007-786-C, Carrollton, Georgia Local Institution - 007-786-A, Cartersville, Georgia Local Institution - 007-786-D, Douglasville, Georgia Local Institution - 007-786-B, Hiram, Georgia Central Georgia Cancer Care - Macon, Macon, Georgia Northwest Georgia Oncology Centers Wellstar - Marietta, Marietta, Georgia Local Institution - 007-897, Honolulu, Hawaii Local Institution - Unk005, Honolulu, Hawaii Local Institution - 007-883-A, Arlington Heights, Illinois Local Institution - 007-955, Chicago, Illinois University of Chicago, Chicago, Illinois Loyola University Medical Center, Maywood, Illinois USOR - Illinois Cancer Specialists - Niles, Niles, Illinois Advocate Medical Group Oncology, Park Ridge, Illinois Local Institution - Unk061, Peoria, Illinois Goshen Center for Cancer Care, Goshen, Indiana Local Institution - 007-942-B, Chanute, Kansas Local Institution - 007-942-D, El Dorado, Kansas Local Institution - 007-942-E, Independence, Kansas Local Institution - 007-942-F, Kingman, Kansas Local Institution - 007-942-G, Liberal, Kansas Local Institution - 007-942-H, McPherson, Kansas MidAmerica Cancer Care - Research, Merriam, Kansas Local Institution - 007-942-I, Newton, Kansas Local Institution - 007-942-J, Parsons, Kansas Local Institution - 007-942-K, Pratt, Kansas Local Institution - 007-942-L, Salina, Kansas Local Institution - 007-942-M, Wellington, Kansas Local Institution - Unk032, Westwood, Kansas Local Institution - 007-942-A, Wichita, Kansas Cancer Center of Kansas - Wichita - Heritage Plaza, Wichita, Kansas Local Institution - 007-942-N, Winfield, Kansas Lexington Medical Cancer Center Hematology/Oncology, Lexington, Kentucky University of Louisville, Louisville, Kentucky Local Institution - 007-388-A, Louisville, Kentucky Local Institution - Unk011, Baton Rouge, Louisiana Local Institution - 007-994-A, Covington, Louisiana Pontchartrain Cancer Center - Covington Office, Covington, Louisiana The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland Dana-Farber Cancer Institute, Boston, Massachusetts Dana-Farber Cancer Institute at St. Elizabeths Medical Center, Brighton, Massachusetts Brigham and Womens/Mass General Health Care Center at Foxborough, Foxborough, Massachusetts Dana-Farber Cancer Institute - Merrimack Valley, Methuen, Massachusetts Dana-Farber Brigham and Womens Cancer Center at Milford Regional, Milford, Massachusetts Dana-Farber Brigham Cancer Center at South Shore Health, South Weymouth, Massachusetts USOR - Minnesota Oncology - Burnsville, Burnsville, Minnesota Local Institution - 007-589A, Edina, Minnesota Local Institution - Unk006, Minneapolis, Minnesota Local Institution - 007-822, Minneapolis, Minnesota Local Institution - 007-830, Rochester, Minnesota Jackson Oncology Associates - The Hederman Cancer Center, Jackson, Mississippi Local Institution - 007-590D, Grand Island, Nebraska Local Institution - 007-590A, Omaha, Nebraska Local Institution - 007-590B, Omaha, Nebraska Nebraska Cancer Specialists - Midwest Cancer Center - Legacy, Omaha, Nebraska Local Institution - 007-590C, Papillion, Nebraska OptumCare Nevada, Las Vegas, Nevada Local Institution - 007-938A, Las Vegas, Nevada Local Institution - 007-938B, Las Vegas, Nevada Local Institution - 007-993, Belleville, New Jersey Astera Cancer Care - East Brunswick, East Brunswick, New Jersey John Theurer Cancer Center, Hackensack, New Jersey Local Institution - 007-975-A, Somerset, New Jersey Local Institution - 007-975-B, Somerset, New Jersey Local Institution - 007-975-C, Somerset, New Jersey Local Institution - 007-975-D, Somerset, New Jersey Holy Name Medical Center, Teaneck, New Jersey New York Oncology Hematology - Albany Medical Center, Albany, New York Local Institution - Unk077, Rhinebeck, New York Montefiore Medical Center, The Bronx, New York Duke University Medical Center, Durham, North Carolina Local Institution - 007-893-B, Cincinnati, Ohio USOR - Oncology Hematology Care - Blue Ash, Cincinnati, Ohio Local Institution - 007-893-C, Cincinnati, Ohio University Hospitals Cleveland Medical Center, Cleveland, Ohio Mark H. Zangmeister Cancer Center, Columbus, Ohio Local Institution - 007-893-A, Fairfield, Ohio Kettering Health Cancer Center - Main Campus, Kettering, Ohio Tricounty Hematology and Oncology - Massillon, Massillon, Ohio USOR - Willamette Valley Cancer Institute and Research Center - Eugene, Eugene, Oregon Local Institution - 007-885B, Portland, Oregon Local Institution - 007-885A, Portland, Oregon Oregon Oncology Specialists, Salem, Oregon Local Institution - 007-885C, Tigard, Oregon Local Institution - Unk041, Allentown, Pennsylvania Veterans Affairs Pittsburgh Healthcare System - University Drive Campus, Pittsburgh, Pennsylvania Local Institution - 007-960, Providence, Rhode Island Local Institution - Unk038, Charleston, South Carolina Local Institution - 007-5475, Spartanburg, South Carolina Avera Cancer Institute, Sioux Falls, South Dakota Local Institution - 007-928-L, Dickson, Tennessee Local Institution - 007-928-J, Franklin, Tennessee Local Institution - 007-928-G, Gallatin, Tennessee West Cancer Center & Research Institute - East Campus, Germantown, Tennessee Local Institution - 007-928-A, Hendersonville, Tennessee Local Institution - 007-928-D, Hermitage, Tennessee Local Institution - 007-928-H, Lebanon, Tennessee Local Institution - 007-928-F, Murfreesboro, Tennessee Local Institution - 007-928-B, Nashville, Tennessee Tennessee Oncology - Nashville - Centennial Clinic - Medical Oncology, Nashville, Tennessee Local Institution - 007-928-K, Nashville, Tennessee Local Institution - 007-928-E, Nashville, Tennessee Local Institution - 007-928-C, Nashville, Tennessee Local Institution - 007-928-M, Shelbyville, Tennessee Local Institution - 007-928-I, Smyrna, Tennessee Local Institution - 007-554B, Abilene, Texas Local Institution - 007-554G, Amarillo, Texas Local Institution - 007-879-A, Arlington, Texas Local Institution - 007-879-B, Arlington, Texas Local Institution - 007-892-B, Austin, Texas Local Institution - 007-892-A, Austin, Texas USOR - Texas Oncology - Dallas Fort Worth (DFW) - South Austin, Austin, Texas Local Institution - 007-879-C, Bedford, Texas Local Institution - Unk059, Dallas, Texas Local Institution - 007-592, Dallas, Texas Texas Oncology - Dallas Fort Worth (DFW) - Baylor Charles A. Sammons Cancer Center, Dallas, Texas USOR - Texas Oncology Northeast Texas - Denison, Denison, Texas Local Institution - 007-554E, El Paso, Texas Local Institution - 007-554C, El Paso, Texas Local Institution - 007-554F, El Paso, Texas USOR - Texas Oncology - Fredericksburg, Fredericksburg, Texas Local Institution - 007-848, Houston, Texas Local Institution - 007-999, Irving, Texas Local Institution - 007-890-B, Longview, Texas Local Institution - 007-554A, Midland, Texas USOR - Texas Oncology - Dallas Fort Worth (DFW) - Odessa West Texas Cancer Center, Odessa, Texas USOR - Texas Oncology - The Woodlands, The Woodlands, Texas Local Institution - 007-890-A, Tyler, Texas Local Institution - 007-554D, Wichita Falls, Texas Local Institution - 007-912, Salt Lake City, Utah Local Institution - 007-814-A, Alexandria, Virginia Local Institution - 007-814-D, Arlington, Virginia USOR - Virginia Cancer Specialists - Fairfax Office, Fairfax, Virginia Local Institution - 007-814-B, Gainesville, Virginia Local Institution - 007-814-C, Leesburg, Virginia Virginia Cancer Institute - West End, Richmond, Virginia USOR - Northwest Cancer Specialists, P.C. dba Compass Oncology - Vancouver Cancer Center, Vancouver, Washington Local Institution - Unk064, Huntington, West Virginia Local Institution - Unk057, Madison, Wisconsin Local Institution - Unk068, Madison, Wisconsin Argentina
Aresma - Clinica Adventista Belgrano, Belgrano, Buenos Aires Fundacion Respirar, Ciudad Autonoma de Buenos Aires, Buenos Aires Local Institution - Unk043, Ciudad Autonoma de Buenos Aires, Buenos Aires Instituto Argentino de Diagnostico y Tratamiento, Ciudad Autonoma de Buenos Aires, Buenos Aires Local Institution - 007-436, Pergamino, Buenos Aires Centro Oncologico Korben, San Pedro, Buenos Aires Instituto de Oncologia de Rosario, Rosario, Santa Fe Province Sanatorio Parque, Rosario, Santa Fe Province Local Institution - Unk053, Buenos Aires Local Institution - 007-5002, Buenos Aires Instituto Oncologico de Cordoba (IONC), Córdoba Local Institution - Unk033, Porto Alegre Local Institution - Unk020, Río Cuarto Australia
Ballarat Regional Integrated Cancer Center, Ballarat Flinders Medical Centre, Bedford Park Local Institution - 007-004, Clayton Canberra Hospital, Garran Icon Cancer Centre, Hyde Park Port Macquarie Base Hospital, Port Macquarie Cancer Care Wollongong, Wollongong Princess Alexandra Hospital, Woolloongabba Austria
Klinikum Klagenfurt Am Worthersee, Klagenfurt Universitatsklinikum Krems, Krems Ordensklinikum Linz Elisabethinen, Linz Medizinische Universitat Wien, Vienna Wiener Gesundheitsverbund - Klinik Hietzing, Vienna Wiener Gesundheitsverbund - Klinik Floridsdorf, Vienna Belgium
Universitair Ziekenhuis Antwerpen, Edegem Algemeen Ziekenhuis Maria Middelares, Ghent Jessa Ziekenhuis - Campus Virga Jesse, Hasselt Local Institution - 007-152, Roeselare Brazil
Local Institution - 007-5050, Salvador, Estado de Bahia Local Institution - 007-458, Natal, Rio Grande do Norte Local Institution - Unk050, Lajeado, Rio Grande do Sul Local Institution - Unk015, Porto Alegre, Rio Grande do Sul Local Institution - 007-5051, Florianópolis, Santa Catarina Local Institution - Unk060, Barretos Local Institution - 007-457, Barretos Local Institution - Unk002, Ijuí Local Institution - 007-459, Porto Alegre Local Institution - Unk003, Rio de Janeiro Local Institution - Unk019, São José do Rio Preto Local Institution - Unk074, São Paulo Bulgaria
Multiprofile Hospital For Active Treatment - Dr. Tota Venkova, Gabrovo Specialized Hospital for Active Oncology Treatment - Haskovo SLLC (SBALO - Haskovo - EOOD), Haskovo Complex Oncology Center - Plovdiv - Base II, Plovdiv University Multiprofile Hospital for Active Treatment St. Ivan Rilski, Sofia Complex Oncology Center - Vratsa, Vratsa Canada
Cross Cancer Institute, Edmonton, Alberta British Columbia Cancer Agency - Vancouver, Vancouver, British Columbia Local Institution - 007-489, London, Ontario Ottawa Hospital - General Campus, Ottawa, Ontario Princess Margaret Cancer Centre, Toronto, Ontario Local Institution - 007-490, Montreal, Quebec Chile
Local Institution - Unk028, Santiago Local Institution - Unk073, Temuco China
Local Institution - 007-051, Bengbu, Anhui The First Affiliated Hospital of Bengbu Medical College/Department of Respiratory and Critical Care Medicine, Bengbu, Anhui Anhui Provincial Hospital, Hefei, Anhui Local Institution - 007-026-Ph2, Hefei, Anhui Local Institution - 007-026, Hefei, Anhui Local Institution - 007-739-Ph2, Hefei, Anhui Local Institution - 007-739, Hefei, Anhui Local Institution - 007-747, Hefei, Anhui Cancer Hospital Chinese Academy of Medical Sciences/Medical Oncology Department, Beijing, Beijing Municipality Local Institution - 007-050, Beijing, Beijing Municipality Local Institution - 007-707-Ph2, Beijing, Beijing Municipality Local Institution - 007-707, Beijing, Beijing Municipality Local Institution - 1025-Ph2, Beijing, Beijing Municipality Colombia
Local Institution - 007-467, Bogotá Local Institution - 007-465, Floridablanca Local Institution - Unk021, Medellín Local Institution - Unk027, Montería Local Institution - 007-466, Valledupar Croatia
Local Institution - 007-4000, Pula Specijalna Bolnica Medico, Rijeka Local Institution - 007-4002, Zagreb Czechia
Multiscan - Ambulance klinicke onkologie se stacionarem - Horovice, Hořovice Fakultni Nemocnice Olomouc, Olomouc Nemocnice AGEL Ostrava-Vitkovice, Ostrava Local Institution - 007-163, Prague Fakultni nemocnice Bulovka, Praha 8 - Liben Denmark
Local Institution - 007-172, Odense Sjukhus Sonderjylland, Sønderborg Sygehus Lillebaelt - Vejle Sygehus, Vejle Finland
Docrates Cancer Center, Helsinki Tampereen Yliopistollinen Sairaala (TAYS), Tampere France
Institut de Cancerologie de lOuest - Angers, Angers Hopital Ambroise-Pare, Boulogne-Billancourt Centre Francois Baclesse, Caen Centre Hospitalier Intercommunal de Creteil, Créteil Hopital Michallon, La Tronche Centre Hospitalier Universitaire Limoges, Limoges Local Institution - 007-1993, Lorient Local Institution - 007-199, Marseille Hopital Nord de Marseille, Marseille Hopital Arnaud de Villeneuve, Montpellier Hopital Emile Muller, Mulhouse Local Institution - 007-1991, Rennes Georgia
Local Institution - 007-790, Batumi Local Institution - 007-065, Tbilisi Local Institution - 007-795, Tbilisi Local Institution - 007-789, Tbilisi Local Institution - 007-063, Tbilisi Institute of Clinical Oncology - Tbilisi, Tbilisi Germany
Local Institution - 007-211A, Immenstadt im Allgäu, Bavaria Local Institution - 007-675, Amberg Local Institution - 007-2222, Augsburg Local Institution - Link, M., Bad Homburg Local Institution - Eggers, H., Braunschweig Klinikum Chemnitz, Chemnitz Kliniken der Stadt Koln, Cologne Klinikum Esslingen, Esslingen am Neckar Krankenhaus Nordwest, Frankfurt am Main Universitatsklinikum Gieen und Marburg - Gieen, Giessen LungenClinic Grosshansdorf, Grohansdorf Asklepios Kliniken Barmbek, Hamburg Local Institution - 007-2229, Hanover Greece
Henry Dunant Hospital Center, Athens, Attica General Hospital for Thoracic Diseases Sotiria, Athens "General Hospital of Athens "Alexandra"", Athens "University General Hospital "Attikon" - General Hospital of West Attica "H Agia Varvara"", Athens University General Hospital of Heraklion (PAGNI), Heraklion University General Hospital of Larissa, Larissa "General Oncology Hospital of Kifisias "Agioi Anargyroi"", Nea Kifissia Metropolitan Hospital, Piraeus Saint Lukes Hospital, Thessaloniki Hong Kong
Humanity & Health Clinical Trial Centre, Central Pamela Youde Nethersole Eastern Hospital, Chai Wan Queen Mary Hospital - Hong Kong, Hong Kong Queen Elizabeth Hospital - Hong Kong, Kowloon Hungary
Semmelweis Egyetem - Pulmonologiai Klinika, Budapest Orszagos Koranyi Pulmonologiai Intezet, Budapest Orszagos Onkologiai Intezet, Budapest Farkasgyepui Tudogyogyintezet, Farkasgyepű Matrai Gyogyintezet, Gyöngyös Local Institution - 007-057, Tatabánya Reformatus Pulmonologiai Centrum, Törökbálint India
Local Institution - 007-1574, Ahmedabad Marathwada Cancer Hospital & Research Institute, Aurangabad Local Institution - 007-1586, Bangalore Local Institution - 007-1575, Belagavi Local Institution - 007-1587, Howrah Local Institution - 007-1564, Hyderabad Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad Local Institution - 007-1569, Jaipur Local Institution - 007-1566, Kochi Netaji Subhas Chandra Bose Cancer Hospital & Research Institute, Kolkata Meenakshi Mission Hospital and Research Centre, Madurai Local Institution - Shetty, R., Mangalore Ireland
Local Institution - 007-256, Cork Beaumont Hospital - Dublin, Dublin St. Jamess Hospital, Dublin Tallaght University Hospital, Dublin University Hospital Galway, Galway Local Institution - 007-258, Limerick University Hospital Waterford, Waterford Israel
Emek Medical Center, Afula Rambam Health Care Campus, Bat Galim Soroka Medical Center, Beersheba Local Institution - 007-263, Holon Shaare Zedek Medical Center, Jerusalem Hadassah University Hospital Ein Kerem, Jerusalem Kaplan Medical Center, Rehovot Tel Aviv Sourasky Medical Center, Tel Aviv Ziv Medical Center, Zsfat Italy
Local Institution - Unk016, Aviano Istituto Tumori Bari Giovanni Paolo II - IRCCS, Bari Azienda Ospedaliero-Universitaria di Bologna - Policlinico Sant Orsola-Malpighi, Bologna Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia, Brescia Istituto di Candiolo - Fondazione del Piemonte per lOncologia, Candiolo Azienda Ospedaliero - Universitaria Careggi, Florence Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale Policlinico San Martino, Genova "Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST", Meldola Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele, Milan Istituto Europeo di Oncologia, Milan Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan Local Institution - 007-318, Monza Japan
National Hospital Organization - Nagoya Medical Center, Nagoya, Aichi-ken Jcho Chukyo Hospital, Nagoya, Chiba Ehime University Hospital, Toon-shi, Ehime Fukushima Medical University Hospital, Fukushima, Fukushima Hyogo Cancer Center, Akashi, Hyōgo Local Institution - 007-1593, Nishinomiya-Shi, Hyōgo Kitasato University Hospital, Sagamihara, Kanagawa Sendai Kousei Hospital, Sendai, Miyagi Nagasaki University Hospital, Nagasaki, Nagasaki Nara Medical University Hospital, Kashihara, Nara National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai-Shi, Osaka National Hospital Organization Iwakuni Clinical Center, Iwakuni Kanazawa University Hospital, Kanazawa
Malaysia
Local Institution - Unk079, Johor Bahru, Johor Hospital Pulau Pinang, George Town, Pulau Pinang Local Institution - Choo Khoon, O., George Town, Pulau Pinang Local Institution - Unk048, George Town, Pulau Pinang Local Institution - Unk007, Petaling Jaya, Selangor Sunway Medical Centre, Petaling Jaya, Selangor Hospital Kuala Lumpur, Kuala Lumpur Local Institution - Unk075, Kuala Lumpur Mexico
Cancer Treatment Clinic and Clinical Trials, Guadalajara, Jalisco Local Institution - Unk070, Guadalajara, Jalisco Local Institution - Unk034, Mexico City, Mexico City Local Institution - Unk049, Mexico City, Mexico City Arke SMO S.A. de C.V., Mexico City Local Institution - Unk037, Monterrey Avix Investigacion Clinica, Monterrey Local Institution - Unk026, Monterrey Netherlands
Het Nederlands Kanker Instituut, Amsterdam Albert Schweitzer Ziekenhuis - Dordwijk, Dordrecht Local Institution - 007-303, Harderwijk Radboud Universitair Medisch Centrum, Nijmegen Erasmus Medisch Centrum, Rotterdam Franciscus Gasthuis & Vlietland - Gasthuis, Rotterdam Local Institution - 007-308, The Hague Universitair Medisch Centrum Utrecht, Utrecht Local Institution - 007-305, Zwolle New Zealand
Health New Zealand - Te Whatu Ora - MidCentral, Palmerston North Norway
Local Institution - 007-310, Drammen Peru
Local Institution - Unk080, Trujillo, La Libertad Local Institution - Unk022, Jesus Maria, Lima region Local Institution - Unk031, Lima Cercado, Lima region Local Institution - Unk024, Miraflores, Lima region Local Institution - Unk042, San Isidro, Lima region Local Institution - Unk071, San Isidro, Lima region Local Institution - Unk054, Surquillo, Lima region Local Institution - Unk051, Arequipa Local Institution - Unk023, Arequipa Local Institution - Unk044, Arequipa Local Institution - Unk040, Cusco Local Institution - Unk046, Lima Philippines
Local Institution - 007-1541, Bacolod City Local Institution - 007-1545, Cebu City Local Institution - 007-1544, Iloilo City Local Institution - 007-1543, Makati City Local Institution - 007-1542, Molo Local Institution - 007-1540, Quezon City Poland
Uniwersyteckie Centrum Kliniczne w Gdansku, Gdansk Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Kielcach, Kielce Pratia MCM Krakow, Krakow MS Pneumed - Janusz Milanowski, Katarzyna Szmygin-Milanowska Spolka Jawna, Lublin Warminsko-mazurskie Centrum Chorob Pluc w Olsztynie, Olsztyn Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy, Otwock Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandow, Poznan Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu, Torun Local Institution - 007-056, Warsaw Local Institution - 007-322, Warsaw Portugal
Unidade Local de Saude de Coimbra, Coimbra Unidade Local de Saude do Alto Ave, E. P. E (Hospital da Senhora da Oliveira Guimaraes), Guimarães Instituto Portugues De Oncologia De Lisboa Francisco Gentil, Lisbon Local Institution - 007-338-A, Lisbon Hospital CUF Descobertas, Lisbon Hospital CUF Porto, Porto Unidade Local de Saude de Santo Antonio, E. P. E - Hospital Geral de Santo Antonio, Porto Local Institution - 007-339, Porto Local Institution - 007-335, Vila Nova de Gaia Romania
Institutul Oncologic Bucuresti - Prof. Dr. Alexandru Trestioreanu, Bucharest Centrul de Radioterapie Amethyst Cluj, Floreşti Centrul de Oncologie Euroclinic, Iași Oncocenter - Oncologie Clinica, Timișoara Serbia
Univerzitetski Klinicki Centar Srbije, Belgrade Institute for Pulmonary Diseases of Vojvodina, Kamenitz Local Institution - 007-694, Kragujevac Uzice General Hospital, Užice Singapore
Raffles Hospital, Singapore Curie Oncology - Farrer - 10-05, Singapore South Africa
Local Institution - 007-4010, Port Elizabeth, Eastern Cape Local Institution - 007-4013, Johannesburg, Gauteng Local Institution - 007-4012, Pretoria, Gauteng South Korea
Inje University Haeundae Paik Hospital, Busan Pusan National University Hospital, Busan Chungbuk National University Hospital, Cheongju-si Kyungpook National University Chilgok Hospital, Daegu National Cancer Center - Korea, Goyang-si Inha University Hospital, Junggu Seoul National University Hospital, Seoul Severance Hospital, Seoul Asan Medical Center, Seoul Samsung Medical Center, Seoul Korea University Guro Hospital, Seoul Catholic University of Korea St. Vincents Hospital, Suwon Spain
Local Institution - 007-611 A, Pamplona, Navarre Complejo Hospitalario Universitario A Coruna, A Coruña Institut Catala dOncologia Badalona, Badalona Hospital de la Santa Creu i Sant Pau, Barcelona Hospital Universitari Dexeus, Barcelona Hospital Universitari Vall dHebron, Barcelona Hospital Clinic de Barcelona, Barcelona Local Institution - Unk081, Bilbao Local Institution - Unk063, Burgos Local Institution - Unk014, Jerez de la Frontera Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas de Gran Canaria Local Institution - Unk012, León Institut Catala dOncologia - Hospital Duran i Reynals (ICO LHospitalet), LHospitalet de Llobregat
Sweden
Local Institution - Unk013, Gävle Switzerland
Local Institution - 007-397, Sankt Gallen Local Institution - 007-396, Villars-sur-Glâne Taiwan
Local Institution - 007-127, Taichung China Medical University Hospital, Taichung Taichung Veterans General Hospital, Taichung National Cheng Kung University Hospital, Tainan Chi Mei Hospital - Liouying, Tainan National Taiwan University Hospital, Taipei Taipei Veterans General Hospital, Taipei Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Chang Gung Memorial Hospital - Linkou Branch, Taoyuan District Thailand
Local Institution - 007-139, Bangkok Navamindradhiraj University - Faculty of Medicine Vajira Hospital, Bangkok Turkey (Türkiye)
Baskent Universitesi Adana Uygulama Ve Arastirma Hastanesi, Alanya T.C. Saglik Bakanligi - Istanbul Il Saglik Mudurlugu - Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi, Altındağ Hacettepe Universitesi Kanser Enstitusu, Ankara Memorial Ankara Hastanesi, Ankara Liv Hospital Ankara, Ankara Local Institution - 007-3810, Antalya VM Medical Park Samsun Hastanesi, Atakum Memorial Bahcelievler Hospital, Bahçelievler Ege Universitesi Tip Fakultesi Hastanesi, Bornova T.C. Saglik Bakanligi Ankara Bilkent Sehi�r Hastanesi�, Çankaya Trakya Universitesi Tip Fakultesi, Edirne Istanbul Universitesi Onkoloji Enstitusu, Fatih Ozel Gaziantep Medical Point Hastanesi, Gaziantep
United Kingdom
University Hospitals Birmingham NHS Foundation Trust, Birmingham Local Institution - 007-415, Edinburgh Local Institution - 007-403, Kent University Hospitals of Leicester NHS Trust, Leicester University College London Hospitals NHS Foundation Trust, London Guys and St Thomas NHS Foundation Trust, London The Christie NHS Foundation Trust, Manchester Royal Surrey County Hospital NHS Foundation Trust, Surrey
Key details Phase
Safety & dosing / Large-scale testing
Sponsor
Mirati Therapeutics Inc.
Enrollment target
~806 participants
Primary completion
October 2028
Age range
18 Years and older
Last updated March 2026
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Local Institution - 007-433, Viedma Local Institution - 1025, Beijing, Beijing Municipality Beijing Cancer Hospital/Thoracic Oncology(2nd) Department, Beijing, Beijing Municipality Beijing Cancer hospital, Beijing, Beijing Municipality Local Institution - 007-027-Ph2, Beijing, Beijing Municipality Local Institution - 007-038-Ph2, Beijing, Beijing Municipality Local Institution - 007-038, Beijing, Beijing Municipality Local Institution - 007-040-Ph2, Beijing, Beijing Municipality Local Institution - 007-040, Beijing, Beijing Municipality Local Institution - 007-718-Ph3, Chongqing, Chongqing Municipality Local Institution - 1029-Ph2, Chongqing, Chongqing Municipality Local Institution - 1029, Chongqing, Chongqing Municipality Chongqing University Three Gorges Hospital/Respiratory Ward of Tumor Center, Chongqing, Chongqing Municipality Local Institution - 007-053, Chongqing, Chongqing Municipality Local Institution - 1046-Ph2, Fuzhou, Fujian Local Institution - 1046, Fuzhou, Fujian Fujian Cancer Hospital, Fuzhou, Fujian Local Institution - 007-039-Ph2, Fuzhou, Fujian Local Institution - 007-039, Fuzhou, Fujian Local Institution - 007-714-Ph2, Xiamen, Fujian Local Institution - 007-714, Xiamen, Fujian Local Institution - 007-732-Ph2, Xiamen, Fujian Local Institution - 007-732, Xiamen, Fujian The First Affiliated Hospital of Xiamen University/Medical Oncology Department, Xiamen, Fujian Local Institution - 1022-Ph2, Guangzhou, Guangdong Local Institution - 1022, Guangzhou, Guangdong Local Institution - 007-712-Ph2, Guangzhou, Guangdong Local Institution - 007-712, Guangzhou, Guangdong The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Local Institution - 007-705-Ph2, Guangzhou, Guangdong Local Institution - 007-705, Guangzhou, Guangdong Nanfang Hospital, Southern Medical University/Respiratory Medicine Department, Guangzhou, Guangdong Local Institution - 007-052, Shenzhen, Guangdong Shenzhen People's Hospital/Department of Respiratory and Critical Care Medicine, Shenzhen, Guangdong Local Institution - 007-704-Ph2, Liuchow, Guangxi Local Institution - 007-704, Liuchow, Guangxi Guangxi Medical University Cancer Hospital/Department of Respiratory Oncology, Nanning, Guangxi Local Institution - 007-384, Nanning, Guangxi Local Institution - 007-744-Ph2, Nanning, Guangxi Local Institution - 1038-Ph2, Nanning, Guangxi Local Institution - 1038, Nanning, Guangxi Local Institution - 007-742, Shijiazhuang, Hebei The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei Cancer Hospital affiliated to Harbin Medical University/Ward 3 of Respiratory Medicine Department, Harbin, Heilongjiang Local Institution - 007-028-Ph2, Harbin, Heilongjiang Local Institution - 007-028, Harbin, Heilongjiang Local Institution - 1012-Ph2, Xinxiang, Henan Henan Cancer Hospital/Second Ward of Respiratory Medicine Department, Zhengzhou, Henan Local Institution - 007-730-Ph3, Zhengzhou, Henan Local Institution - 1010-Ph2, Zhengzhou, Henan Local Institution - 1010, Zhengzhou, Henan Local Institution - 007-021-Ph2, Zhengzhou, Henan Local Institution - 007-715-Ph2, Zhengzhou, Henan Local Institution - 007-715, Zhengzhou, Henan Local Institution - 007-730-Ph2, Zhengzhou, Henan Local Institution - 007-719-Ph2, Wuhan, Hubei Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology/Cancer Center Department, Wuhan, Hubei Local Institution - 007-700-Ph2, Wuhan, Hubei Local Institution - 007-700, Wuhan, Hubei Local Institution - 007-701-Ph2, Changsha, Hunan Hunan Cancer Hospital/Thoracic Medicine Department II, Changsha, Hunan Local Institution - 1021-Ph2, Nanjing, Jiangsu Local Institution - 1021, Nanjing, Jiangsu Nanjing First Hospital/Department of Respiratory and Critical Care Medicine, Nanjing, Jiangsu Nanjing First Hospital/Respiratory Department, Nanjing, Jiangsu Local Institution - 1018-Ph2, Nanjing, Jiangsu Local Institution - 1018, Nanjing, Jiangsu Local Institution - 1020-Ph2, Nanjing, Jiangsu Local Institution - 1020, Nanjing, Jiangsu Local Institution - 1004-Ph2, Nantong, Jiangsu Local Institution - 1004, Nantong, Jiangsu Local Institution - 1017-Ph2, Xuzhou, Jiangsu Local Institution - 1017, Xuzhou, Jiangsu Local Institution - 007-713-Ph2, Nanchang, Jiangxi Local Institution - 1040-Ph2, Nanchang, Jiangxi Local Institution - 1040, Nanchang, Jiangxi The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Local Institution - 1006-Ph2, Changchun, Jilin Local Institution - 1006, Changchun, Jilin Local Institution - 007-717-Ph2, Changchun, Jilin The First Bethune Hospital Of Jilin University/Oncology Department, Changchun, Jilin Local Institution - 007-741-Ph2, Shenyang, Liaoning Local Institution - 007-741, Shenyang, Liaoning Local Institution - 1008-Ph2, Shenyang, Liaoning Local Institution - 1008, Shenyang, Liaoning Local Institution - 007-749, Shenyang, Liaoning Shengjing Hospital of China Medical University, Shenyang, Liaoning Local Institution - 007-702-Ph2, Shenyang, Liaoning Local Institution - 007-702, Shenyang, Liaoning Local Institution - 007-746-Ph3, Yinchuan, Ningxia Local Institution - 007-746, Yinchuan, Ningxia Local Institution - 007-718-Ph2, Xi'an, Shaanxi Local Institution - 007-721-Ph2, Xi'an, Shaanxi Local Institution - 007-721, Xi'an, Shaanxi The First Affiliated Hospital of Xi'an Jiaotong University/Medical Oncology Department, Xi'an, Shaanxi Local Institution - 007-708-Ph2, Jinan, Shandong Shandong Cancer Hospital, Jinan, Shandong Local Institution - 007-737-Ph2, Linyi, Shandong Linyi Cancer Hospital/Oncology Department, Linyi, Shandong Local Institution - 007-703-Ph2, Linyi, Shandong Local Institution - 007-703, Linyi, Shandong Local Institution - 007-709-Ph2, Shanghai, Shanghai Municipality Local Institution - 007-709, Shanghai, Shanghai Municipality Shanghai Chest Hospital-Oncology department, Shanghai, Shanghai Municipality Fudan University Shanghai Cancer Center/Thoracic Oncology Department, Shanghai, Shanghai Municipality Local Institution - 007-024-Ph2, Shanghai, Shanghai Municipality Local Institution - 007-024-Ph3, Shanghai, Shanghai Municipality Local Institution - 007-024, Shanghai, Shanghai Municipality Local Institution - 007-035-Ph2, Shanghai, Shanghai Municipality Local Institution - 007-740-Ph2, Taiyuan, Shanxi Local Institution - 007-740, Taiyuan, Shanxi Local Institution - 007-748, Taiyuan, Shanxi Shanxi Provincial Cancer Hospital/Respiratory Medicine, Taiyuan, Shanxi Local Institution - 007-710-Ph2, Chengdu, Sichuan Local Institution - 007-710, Chengdu, Sichuan Local Institution - 007-720-Ph2, Chengdu, Sichuan Sichuan Cancer hospital, Chengdu, Sichuan West China Hospital of Sichuan University, Chengdu, Sichuan Local Institution - 007-711-Ph2, Luzhou, Sichuan Local Institution - 007-711, Luzhou, Sichuan Xinjiang Medical University Cancer Hospital - Urumqi, Ürümqi, Xinjiang Local Institution - 007-743, Ürümqi, Xinjiang Local Institution - 1036-Ph2, Ürümqi, Xinjiang Local Institution - 1036, Ürümqi, Xinjiang Local Institution - 1032-Ph2, Kunming, Yunnan Local Institution - 1032, Kunming, Yunnan Local Institution - 007-385-Ph3, Kunming, Yunnan Local Institution - 007-385, Kunming, Yunnan Local Institution - 007-745-Ph2, Kunming, Yunnan Local Institution - 007-745, Kunming, Yunnan Local Institution - 007-716-Ph2, Hangzhou, Zhejiang Local Institution - 007-716, Hangzhou, Zhejiang The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Local Institution - 007-036-Ph2, Hangzhou, Zhejiang Local Institution - 007-036, Hangzhou, Zhejiang Local Institution - 007-037-Ph2, Hangzhou, Zhejiang Zhejiang Cancer Hospital, Hangzhou, Zhejiang Local Institution - 1050-Ph2, Taizhou, Zhejiang Local Institution - 1050, Taizhou, Zhejiang Taizhou Hospital Of Zhejiang Province, Taizhou, Zhejiang Local Institution - 1043-Ph2, Qingdao Local Institution - 1043, Qingdao Local Institution - 007-035, Shanghai Centre Hospitalier Universitaire De Nantes - Hopital Nord Laennec, Saint-Herblain Institut de Cancerologie de lOuest - Saint-Herblain - Site Rene Gauducheau, Saint-Herblain Les Hopitaux Universitaires de Strasbourg, Strasbourg Hopital Bretonneau, Tours Local Institution - 007-202, Villejuif Local Institution - 007-677, Heidelberg
Local Institution - 007-673, Heilbronn Lungenklinik Hemer, Hemer Local Institution - 007-225, Jena Westpfalz-Klinikum - Kaiserslautern, Kaiserslautern Klinikverbund Allgau - Klinikum Kempten, Kempten Local Institution - 007-2230, Krefeld SLK-Kliniken - Fachklinik Lowenstein, Löwenstein Universitatsklinikum Schleswig-Holstein - Campus Lubeck, Lübeck Local Institution - 007-223, Mainz Kliniken Maria Hilf, Mönchengladbach Local Institution - 007-2228, München Munchen Klinik Bogenhausen, München Ruppiner Kliniken GmbH, Neuruppin Sana Klinikum Offenbach, Offenbach Pius-Hospital Oldenburg, Oldenburg Local Institution - 007-2226, Treuenbrietzen Local Institution - 007-2227, Trier Bundeswehrkrankenhaus Ulm, Ulm Tata Memorial Centre - Tata Memorial Hospital, Mumbai
Mysore Medical College and Research Institute, Mysore Local Institution - 007-1588, New Delhi Indraprastha Apollo Hospitals, New Delhi Local Institution - 007-1578, New Delhi Indira Gandhi Institute of Medical Sciences, Patna Local Institution - 007-1571, Pune Nirmal Hospital Pvt. Ltd., Rajkot Mahamana Pandit Madan Mohan Malviya Cancer Centre, Varanasi Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Naples
Istituto Oncologico Veneto - IRCCS, Padova Local Institution - Unk017, Padova Azienda Ospedaliero-Universitaria di Parma, Parma Azienda Ospedaliera di Perugia - Santa Maria della Misericordia, Perugia Azienda Sanitaria Territoriale Pesaro Urbino, Pesaro Ospedale Santa Maria delle Croci di Ravenna, Ravenna Istituto Nazionale Tumori Regina Elena, Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma Local Institution - Unk030, Rozzano Ospedale di Circolo e Fondazione Macchi, Varese Kochi Medical School Hospital, Nankoku-shi
Osaka City General Hospital, Osaka Osaka Prefectural Hospital Organization - Osaka International Cancer Institute, Osaka Local Institution - 007-1164, Toyama Clinica Universidad de Navarra - Madrid, Madrid
Hospital Universitario Ramon y Cajal, Madrid Hospital Clinico San Carlos, Madrid Hospital Universitario Fundacion Jimenez Diaz, Madrid Hospital Universitario 12 de Octubre, Madrid Hospital Regional Universitario de Malaga - Hospital Civil, Málaga Local Institution - 007-604, Santander Hospital Clinico Universitario de Santiago, Santiago de Compostela Hospital Universitario Virgen del Rocio, Seville Hospital Clinico Universitario de Valencia, Valencia Hospital Universitari i Politecnic La Fe, Valencia Local Institution - 007-069, Istanbul
Istanbul Onkoloji Hastanesi, Istanbul Izmir Ekonomi Universitesi Medical Point Hastanesi, Izmir Yeditepe Universitesi Kosuyolu Hastanesi, Kadıköy Kocaeli Universitesi Arastirma ve Uygulama Hastanesi, Kocaeli Inonu Universitesi Turgut Ozal Tip Merkezi, Malatya Ankara Universitesi Tip Fakultesi - Cebeci Arastirma ve Uygulama Hastanesi, Mamak Istanbul Universitesi Cerrahpasa Tip Fakultesi Hastanesi, Şişli