Plain-English translation of NCT04614194 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers want to understand how your immune system fights hormone-sensitive breast cancer, and whether adding to standard hormone therapy can boost that immune response. You would take these medications for just 2 weeks before starting your regular cancer treatment, while doctors collect tissue and blood samples to study how your body responds.
Right now, doctors know hormone therapy works for some breast cancers, but they don't fully understand how to make the immune system fight harder against these tumors. This study aims to uncover those answers so future patients might benefit from better, more personalized treatment options.
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You would take one or both study medications (depending on which group you're assigned to) for 2 weeks before your scheduled surgery or standard cancer treatment begins. Before starting, you'd have a small tissue biopsy and blood draw for research purposes. After 2 weeks, you'd have another biopsy and blood draw so doctors can compare how your immune system changed. Then you'd proceed with your regular cancer care.
AI-generated summary from trial data · Sep 1, 2026 · Not medical advice
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