Plain-English translation of NCT04623099 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Anxiety research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether using a teenager's genetic information to personalize the dose of —a common anxiety medication—works better than giving everyone the same dose. The study will compare two approaches: one where all teens take a standard dose that increases over time, and another where the dose is adjusted based on how each teen's body processes the medication. The goal is to find out which approach helps anxiety more effectively and with fewer side effects.
Not all teens respond the same way to the same medication dose—some have side effects while others don't get relief. This medication has genetic factors that affect how fast a person's body breaks it down, which means the right dose varies from person to person. This study hopes to show that tailoring the dose to match each teen's genetics could lead to better results and fewer problems.
You likely qualify if…
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You will have two screening visits to confirm you qualify, then be randomly assigned to receive either standard dosing or personalized dosing based on your genes. You'll take the medication daily for 12 weeks, starting with a low dose that may increase depending on your group. Throughout the study, you'll attend follow-up visits where your doctor will check how well the medication is working, ask about any side effects, and run some simple tests. A parent or guardian will need to help monitor your progress and bring you to appointments.
AI-generated summary from trial data · Jul 14, 2026 · Not medical advice
United States