Plain-English translation of NCT04653012 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is designed to help doctors better understand how seizures happen in the brain. Researchers will use special recording electrodes (called macro-micro electrodes) that are already being placed in your brain as part of your regular presurgical evaluation for epilepsy. While these electrodes are in place, the research team will record your brain activity not only during seizures, but also during sleep and while you're doing thinking tasks — all to learn more about how epilepsy works.
Many people with epilepsy don't respond well to seizure medications, and surgery may be an option. To plan surgery safely and effectively, doctors need to understand exactly where seizures start and how they spread through the brain. This study aims to provide that detailed information so that surgery can be more precise and help more patients.
You likely qualify if…
You likely don't qualify if…
Since you are already undergoing presurgical evaluation with intracranial electrodes, participation in this study means allowing the research team to use the recordings from those same electrodes to study your brain activity in more detail. You will have the electrodes implanted as part of your standard clinical care, and researchers will record your brain patterns while you rest, sleep, and perform simple thinking tasks. There is no additional surgery or implantation beyond what you're already having done for your epilepsy evaluation.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
France
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Enrollment target
~50 participants
Started
February 2021
Primary completion
February 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Vincent Navarro
Institut National de la Santé Et de la Recherche Médicale, France
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.