Plain-English translation of NCT04656080 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Researchers are studying a blood test called AlloSure that helps detect rejection in heart transplant recipients. This trial is testing whether the test stays reliable after patients do strenuous exercise, and whether it works equally well in transplants that experienced longer preservation times before surgery.
The AlloSure blood test is a useful tool for monitoring heart transplant health, but doctors need to know whether intense physical activity affects the results, so they can trust the test in all situations and for all types of transplants.
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You will visit the research site to have blood drawn, then perform a maximal exercise test on a treadmill or stationary bike (similar to a stress test your cardiologist may have ordered). After exercise, additional blood samples will be collected at specific time points to measure how the blood test responds. The study enrolls two groups: recent transplant recipients without rejection, and transplant recipients with treated rejection.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States
Enrollment target
~27 participants
Started
May 2020
Primary completion
December 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
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Central contact
Aayla Jamil, MBBS MPH
BSWRI
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