Plain-English translation of NCT04665635 on ClinicalTrials.gov ↗ · Source last updated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two surgical approaches for women with advanced epithelial ovarian cancer that has spread to the rectosigmoid colon (the lower part of the large intestine). One approach removes the affected section of colon entirely, while the other carefully removes just the tumor tissue while preserving the colon. The study aims to determine which method leads to better outcomes and fewer complications.
Ovarian cancer frequently spreads to the rectosigmoid colon, and surgeons currently use two different techniques to treat this spread. While both methods are used successfully, there is no clear evidence from rigorous studies comparing which approach is safer and more effective for patients.
You likely qualify if…
You likely don't qualify if…
If you qualify and enroll, you will undergo ovarian cancer surgery performed by your surgical team. During surgery, if the tumor involves only the outer layers of the rectosigmoid colon, you will be randomly assigned to receive either rectosigmoid resection (surgical removal of the affected colon segment) or seromuscular tumor shaving (careful removal of only the tumor tissue). After surgery, you will continue with standard ovarian cancer chemotherapy and follow-up care as recommended by your doctors.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
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