Plain-English translation of NCT04666402 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a new approach to liver disease diagnosis that combines multiple blood tests and imaging scans together—rather than using each test alone—to spot liver disease much earlier. Researchers are building software that learns from all this combined information to create a smarter tool for detecting disease and scarring before they become dangerous. If successful, this could help catch liver disease when treatment is still possible.
Liver disease is very common but often goes undetected until it's too advanced to treat. Right now, doctors use single tests that don't catch disease early enough. This study aims to solve that problem by combining multiple tests into one smarter system that can find liver disease sooner.
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If you join this study, you would attend a Community Liver Assessment Clinic where you'll have routine blood tests and imaging scans as part of your regular care. The study collects all of this information—along with a few additional non-invasive tests—into a shared database that researchers use to build and improve the new diagnostic tool. There is no separate medication or invasive procedure; you're contributing your test results to help train the system to spot liver disease earlier in future patients.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United Kingdom
Sponsor
Manchester University NHS Foundation Trust
Collaborators
University of Manchester, University of Nottingham
Enrollment target
~1,200 participants
Started
October 2020
Primary completion
March 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Varinder Athwal
Manchester University NHS Foundation Trust/Manchester University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.