Plain-English translation of NCT04667585 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a PET scan taken about two weeks into radiation therapy can help doctors identify patients who are responding well to treatment and safely lower their radiation dose. You would receive standard chemotherapy and radiation therapy, but the PET scan results may allow your doctors to give you less total radiation if you're responding well. This approach aims to maintain your cure rates while reducing side effects from radiation exposure.
Current radiation therapy for HPV-related throat cancer works well but can cause long-term side effects. This trial exists to see if doctors can use imaging during treatment to identify patients who are doing well enough to safely receive lower radiation doses, potentially reducing harm while keeping the same cure rates.
You would receive standard radiation therapy and chemotherapy as planned. About two weeks into your radiation treatment, you would receive a PET scan (a special imaging test that shows how your cancer is responding). Based on your scan results, your doctor may keep your radiation dose at the standard level or lower it if your cancer is responding well. You would continue your treatment plan and have follow-up visits to monitor your progress.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States