Plain-English translation of NCT04692337 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether placing a small reservoir (called an Ommaya reservoir) under your scalp during brain tumor surgery can help doctors collect spinal fluid samples more easily in the future. Right now, collecting these samples usually requires an uncomfortable needle procedure. By placing this small device during your planned surgery, researchers hope to make it simpler to gather samples over time to better understand your tumor and test new treatments.
Brain tumors are hard to treat, and progress in developing better therapies has been slow. Researchers believe that collecting spinal fluid samples at multiple points over time could reveal important information about how your tumor is changing and how well treatments are working — but the current methods of collecting these samples are inconvenient and uncomfortable, which discourages patients from participating in research.
You likely qualify if…
You likely don't qualify if…
If you join this study, the Ommaya reservoir will be placed under your scalp during your planned brain tumor surgery — it's a small addition to the procedure you're already having. After surgery, whenever researchers need to collect spinal fluid samples, they can easily access the reservoir instead of doing an uncomfortable needle procedure. You'll need to agree to let them collect samples at least two more times, and those samples will be stored and used for multiple research projects to help doctors better understand and treat brain tumors.
AI-generated summary from trial data · Aug 18, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Collaborators
National Institute of Neurological Disorders and Stroke (NINDS), National Cancer Institute (NCI)
Enrollment target
~100 participants
Started
January 2021
Primary completion
February 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Essa Sharif
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.