Adding Targeted Local Treatment to Standard Therapy for Advanced Breast Cancer

This trial is testing whether adding local treatments—like surgery, radiation therapy, or radiofrequency ablation—to standard systemic therapy can help women with hormone-receptor-positive breast cancer that has spread to a limited number of sites (oligometastatic disease). The study compares two approaches: continuing standard therapy alone, or combining standard therapy with local treatment targeted at the areas where cancer has spread. The goal is to see if treating these specific spots directly can improve long-term outcomes.

For patients whose cancer has spread to only a few sites but remains controlled on standard therapy, it's unclear whether adding local treatment to those specific spots offers a real benefit. This trial aims to answer that question and help doctors decide the best approach for patients in this situation.