Plain-English translation of NCT04699591 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing , a medication that helps the stomach move food through more normally, for teenagers and young adults (ages 12–21) whose severe reflux, nausea, vomiting, or digestion problems have not gotten better with standard treatments. The medication is taken four times a day, with the dose adjusted based on your weight. The study will track how well this treatment works and monitor your health closely with regular check-ups, blood tests, and heart monitoring.
Many young people struggle with severe stomach problems and acid reflux that don't respond to the usual medications available. This trial exists to see whether this medication, which is used in other countries, could help patients in the United States who are suffering and have run out of other options.
You likely qualify if…
You likely don't qualify if…
You will start with screening tests—a physical exam, heart tracing (ECG), and blood work—to make sure the medication is safe for you. If you qualify, you will take the medication four times each day, with your dose based on your weight. For the first year, you will return every two months for check-ups that include a physical exam, blood tests, and heart monitoring; if your dose increases at any time, you'll have an extra heart tracing. After the first year, if the medication is helping, you will continue taking it and have check-ups every six months until you and your doctor decide to stop.
AI-generated summary from trial data · Aug 19, 2026 · Not medical advice
United States
Sponsor
Jose Cocjin
Enrollment target
~20 participants
Started
April 2013
Primary completion
December 2035
Age range
12 Years – 21 Years
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Corey Schurman, MA, CCRC
Children's Mercy Hospital Kansas City
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.