Plain-English translation of NCT04701671 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Project THINK is following 180 children and teens for 18 months to understand how their brain's ability to control impulses and make decisions affects their weight and eating habits. The researchers want to learn whether children with weaker self-control abilities in the brain—both in general and specifically around food—are more likely to gain weight and experience episodes of uncontrolled eating. Some participants will also have brain scans (MRI) to see how their brains respond to food-related decisions.
Childhood obesity and loss-of-control eating are serious health problems, but we don't fully understand why some children struggle more than others. This research aims to identify the brain-based differences that put certain children at higher risk, which could eventually help doctors offer better prevention and treatment.
You will visit the research center at the beginning of the study and again 18 months later. At these visits, you'll complete computer-based tests that measure how well you can control impulses and make decisions, especially around food. Some participants (randomly selected) will also have a brain scan (MRI) at both visits—a painless imaging test that takes about an hour. You'll answer questions about your eating habits and your weight will be measured. The study lasts 18 months total, with most of the intensive testing happening at the start and end.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States