Recruiting

Faster stroke treatment using imaging in the operating room

Plain-English translation of NCT04701684 on ClinicalTrials.gov ↗ · Source last updated March 2026 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

When someone has a stroke caused by a blood clot, every minute counts. This trial is testing a new workflow that diagnoses and treats stroke patients all in one place—the interventional operating room—using specialized imaging equipment called Cone-Beam CT. The goal is to get patients treated faster than the traditional approach, which involves scanning in one location and then moving to another area for treatment.

Stroke outcomes depend heavily on how quickly patients receive treatment. The current standard approach involves delays because patients need imaging in one place, then must be moved to another location for treatment. This trial is exploring whether doing everything in the operating room from the start could eliminate those delays and improve patient outcomes.

Do you qualify?

You likely qualify if…

you are 18 years old or older
you arrived at the hospital within 6 hours of stroke symptoms starting, or you had a wake-up stroke discovered within 6 hours of arriving at the hospital
you have moderate to severe stroke symptoms (a baseline score of 10 or higher on a standard stroke severity scale)
you were independent in your daily activities before the stroke (not severely disabled or requiring constant care)
the operating room and treatment team are immediately available at your hospital

You likely don't qualify if…

you have a bleeding disorder or are taking blood thinners at high doses (INR greater than 3.0)
you have a very low platelet count (less than 30,000)
you have severely high blood pressure that cannot be controlled with medication
you have a serious allergy to contrast dye (more than a rash)
you have a serious illness with a life expectancy of less than one year

What participation looks like

If you qualify and agree to participate, you will be randomly assigned to either the new direct operating room workflow or the standard imaging-then-treatment approach. Regardless of which group you join, you will receive appropriate stroke treatment at the hospital. The study will track your recovery and outcomes for 90 days after your stroke, with a follow-up visit or contact to assess how well you have recovered.

AI-generated summary from trial data · Jun 7, 2026 · Not medical advice

Trial locations(23 sites)

United States

Baptist Medical Center, Jacksonville, Florida

Grady Memorial Hospital/Emory University, Atlanta, Georgia

Montefiore Medical Center, The Bronx, New York

Argentina

La Sagrada Familia Clinic, José Hernández

Belgium

UZ Brussels, Brussels