Plain-English translation of NCT04712656 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at how CPAP therapy — a common breathing machine used to treat obstructive sleep apnea — affects your blood pressure and heart health over time. Researchers will compare people who use CPAP regularly with those who don't use it, to understand whether the treatment actually helps protect your heart. The study will follow you for up to 10 years with regular check-ins.
Sleep apnea is known to strain the heart and raise blood pressure, but doctors aren't completely sure how much using CPAP actually helps prevent heart problems like heart attacks and strokes. This study aims to answer that important question so patients and doctors can make better treatment decisions.
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You would start by completing initial tests including blood work, blood pressure monitoring over 24 hours, heart rhythm recordings, and questionnaires about your health and lifestyle. Then you would begin using CPAP therapy as your doctor recommends. After 6 months, you would repeat some of the same tests to see if anything has changed. After that, the researchers will call you once a year for 10 years to ask whether you're still using CPAP, if you've had any heart problems, and if your medications have changed.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
Ohio State University
Collaborators
University of Pennsylvania, Chang Gung Memorial Hospital
Enrollment target
~1,739 participants
Started
March 2021
Primary completion
March 2031
Age range
30 Years – 75 Years
Last updated on clinicaltrials.gov in July 2025.
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Central contact
ALICIA GONZALEZ ZACARIAS, MD
Ohio State University
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