Plain-English translation of NCT04715984 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand why some people with Parkinson's disease develop problems with memory and thinking. This study will record brain activity from specific brain areas during deep brain stimulation surgery — a procedure you may already be having for Parkinson's motor symptoms. By measuring this brain activity, scientists hope to learn what causes these cognitive problems so better treatments can be developed.
Currently, doctors don't fully understand why cognitive problems happen in Parkinson's disease or how to predict who will experience them. This research aims to fill that gap by directly measuring brain activity in the areas involved in thinking and memory.
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If you qualify and are already scheduled for deep brain stimulation surgery at Vanderbilt, the research team will record brain activity from specific areas while you are awake during your surgery. You'll be asked to respond to simple instructions or tasks while these recordings happen. The study uses the surgery you're already having — it doesn't require additional procedures or separate visits.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
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