Plain-English translation of NCT04717388 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating how tinnitus — the persistent ringing, buzzing, or noise in the ears that only you can hear — affects your brain, thinking abilities, and emotional wellbeing. Researchers want to understand why some people develop tinnitus, especially after certain types of brain surgery, and how it changes the way different parts of the brain work together. By comparing people with tinnitus to those without it, and looking at brain imaging, the study aims to better understand what causes this condition and how it impacts daily life.
Tinnitus can be deeply disabling, causing anxiety, depression, sleep problems, and difficulty concentrating — yet scientists still don't fully understand how it develops or why it affects some people more severely than others. This study exists to fill that gap by examining the brain changes linked to tinnitus and exploring whether a specific type of brain surgery for epilepsy might increase the risk of developing it.
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You will complete hearing tests, thinking and memory assessments, and questionnaires about your mood and quality of life. Some participants will also undergo an MRI brain scan to help researchers see how different brain regions connect and function. The study compares four groups: people with tinnitus who had brain surgery, people with tinnitus who did not have surgery, people without tinnitus who had brain surgery, and healthy people without tinnitus or surgery. The visits and exact duration will depend on which group you join.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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