Plain-English translation of NCT04724941 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →The PASS-PP Study is a long-term research program designed to identify people who may be at risk of developing Parkinson's disease before any symptoms appear. Researchers are studying biomarkers—measurable signs in the blood and other tissues—along with detailed information about non-motor symptoms (like sleep problems, mood changes, and other signs that aren't movement-related) to predict who might develop this disease. By following participants over time, the study aims to improve our ability to spot Parkinson's disease very early.
Parkinson's disease often progresses silently for years before movement symptoms appear. This study exists to catch the disease at its earliest stages when people might benefit from preventive treatments, and to better understand which individuals are truly at risk so we can offer them support and monitoring before symptoms develop.
You likely qualify if…
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You would visit the neurology department once a year for a detailed medical history, neurological exam, and movement assessment. Between visits, you'd provide blood samples every six months and complete quick online surveys about non-motor symptoms (like sleep quality, mood, and digestion) every three months. The study is observational, meaning researchers are watching and measuring rather than giving you any new medication. If you choose, you can also participate in an optional substudy involving a spinal fluid test every two years.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
Germany
Sponsor
University Hospital Schleswig-Holstein
Collaborators
UCB Biopharma SRL, University of Kiel
Enrollment target
~2,000 participants
Started
June 2021
Primary completion
December 2027
Age range
50 Years – 99 Years
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Eva Schaeffer, Dr.
Department for Neurology, University of Kiel
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.