Plain-English translation of NCT04727489 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are trying to understand which genetic changes in the brain might be linked to autism spectrum disorder. This study will collect blood samples from about 3,800 people — including children and adults with autism, their family members, and people without autism — to look for patterns in their DNA. By comparing genetic information across families, scientists hope to discover which genes play a role in autism and how they might affect the brain.
Many cases of autism appear to run in families, suggesting genetics play a role, but scientists still don't fully understand which specific genes are involved or how they cause autism. This research aims to fill that gap by studying the genes related to how brain cells communicate with each other — knowledge that could eventually lead to better understanding and treatment of autism.
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If you join this study, you will have a blood sample taken once, which researchers will use for genetic testing. You may also be asked to share medical information or family history to help scientists understand patterns in how autism appears across generations. For those with autism, trained specialists will conduct formal diagnostic assessments using standard interviews and observation tools. The study is based in France and involves collaborating research centers.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
France