Plain-English translation of NCT04748237 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether getting a CT heart scan (coronary computed tomographic angiography, or CCTA) early helps doctors better care for people with chest pain who may have heart disease. About 1,600 people will be randomly assigned to either receive an early heart scan or follow the standard care approach without an early scan. The goal is to see which approach helps prevent serious heart problems like heart attacks.
When people come to the emergency room with chest pain, doctors aren't always sure right away whether it's caused by a blocked heart artery or something else. This trial is trying to figure out whether getting a detailed heart scan early on—rather than waiting for other tests—helps doctors make better decisions faster and keep patients safer.
You likely qualify if…
You likely don't qualify if…
If you join this study, you'll be randomly assigned to one of two groups. One group will receive a heart CT scan as soon as possible (usually within 24 hours). The other group will receive standard care, which may include other heart tests like an exercise test or stress echocardiogram, depending on what your doctor recommends. All participants will be monitored for serious heart events like heart attacks or the need for further treatment over time.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Sweden
Sponsor
Karolinska Institutet
Enrollment target
~1,600 participants
Started
January 2021
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Liselotte Persson, RN
Karolinska Institutet
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.