FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)

Active, not recruiting

Plain-English translation of NCT04768972 on ClinicalTrials.gov ↗ · Source last updated July 2026 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

Trial locations(25 sites)

United States

University of California San Diego, La Jolla, California

Stanford University Medical Center, Palo Alto, California

Johns Hopkins University, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Washington University School of Medicine, St Louis, Missouri