Plain-English translation of NCT04770207 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new approach to treat advanced cancers using tiny beads called DC-Beads that are loaded with multiple cancer-fighting drugs. The beads are injected directly into your tumor under imaging guidance, delivering high doses of medication right where the cancer is. Depending on your previous treatments, you may receive beads loaded with different combinations of chemotherapy drugs and immune-boosting medications.
Many people with advanced cancers have tumors that stop responding to standard immunotherapy treatments. This trial is exploring whether delivering multiple types of cancer-fighting drugs directly into the tumor—rather than throughout the whole body—might work better, especially for patients whose previous treatments have failed.
You likely qualify if…
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You would receive an injection of the drug-loaded beads directly into your tumor using CT imaging to guide placement—a minimally invasive procedure. The specific combination of drugs in your beads would depend on which immunotherapy treatments you've previously received. After the injection, doctors would monitor you for side effects and measure how well the treatment is working using standard imaging assessments.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
China
Phase
Testing effectiveness
Sponsor
Second Affiliated Hospital of Guangzhou Medical University
Enrollment target
~100 participants
Started
November 2020
Primary completion
November 2029
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Bingjia He, MD
Second Affiliated Hospital of Guangzhou Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.