Plain-English translation of NCT04775355 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how the bacteria living in your gut and urinary system change when you receive radiation therapy and hormone therapy for prostate cancer. By studying these bacterial communities before, during, and after your cancer treatment, doctors hope to learn whether certain bacteria patterns can predict who is more likely to experience side effects like urinary or bowel problems.
Radiation therapy and hormone therapy for prostate cancer can cause uncomfortable side effects in the urinary and digestive systems. Scientists believe that the trillions of bacteria naturally living in your body may play a role in determining how severe these side effects become. Understanding these bacterial changes could one day help doctors predict and prevent side effects before they happen.
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You will provide stool and urine samples at three key times: before your cancer treatment starts, after hormone therapy but before radiation begins, and after radiation therapy ends. You'll also complete questionnaires about any side effects or symptoms before radiation starts, halfway through treatment, and then at follow-up visits over the next 3 years. Your medical records will be reviewed by the research team to track your treatment and outcomes.
AI-generated summary from trial data · Oct 25, 2026 · Not medical advice
United States