Plain-English translation of NCT04776330 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Myeloma research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing a new treatment called BCMA-targeted prime CAR-T cell therapy for people with multiple myeloma (a blood cancer) that hasn't responded well to standard treatments. Researchers have engineered immune cells to recognize and attack cancer cells, then infuse them back into your body. The study will measure whether this treatment is safe and whether it helps control the cancer.
Multiple myeloma can become resistant to standard chemotherapy and other treatments, leaving patients with few options. This medication targets a specific marker found on myeloma cancer cells, potentially offering a new path for people whose disease has come back or stopped responding to other therapies.
You likely qualify if…
You likely don't qualify if…
You will receive the engineered immune cells through an infusion at the study center. Before treatment, you'll have blood work and heart function tests to make sure you're healthy enough to proceed. After the infusion, researchers will monitor you closely with regular visits and blood tests to watch for side effects and see how well the treatment is working.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
China