Plain-English translation of NCT04787042 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is one of the first times this treatment has been tested in people.
This is an early-stage clinical trial testing , a new medication designed to activate your immune system to fight cancer. The trial has two parts: first, researchers will figure out the safest and most effective dose by gradually increasing it in small groups of patients; then, they will test whether this medication works against specific types of advanced cancer, either alone or combined with other cancer treatments.
Many patients with advanced solid tumors stop responding to standard cancer treatments or cannot tolerate them. This medication takes a different approach by boosting the body's own immune system to recognize and attack cancer cells, which may help patients who have run out of other options.
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In the first part of the trial, you will receive weekly injections or infusions of the medication starting at a low dose, with the dose gradually increasing in small groups until researchers find the safest level. In the second part, you will receive the medication at the dose determined to be best, and your tumors will be measured every 8 to 12 weeks to see if the treatment is working. Throughout the study, you will have regular check-ups, blood tests, and tumor biopsies to monitor your safety and how your body is responding.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
United States