Plain-English translation of NCT04792320 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether CharXenPlus (an activated bamboo charcoal supplement) combined with probiotics can help people who have both chronic kidney disease and poor blood flow in their legs. Researchers believe that harmful toxins build up in the gut when kidneys don't work well, and that this contributes to dangerous blood vessel problems. This study will test whether this medication can reduce those toxins and improve blood vessel health.
People with chronic kidney disease often develop serious problems with their blood vessels, which can lead to amputations, heart attacks, and death. Current treatments don't always work well enough, so researchers want to see if this new treatment approach using natural substances that work with your body's beneficial bacteria might prevent these dangerous complications.
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You would visit the research hospital several times over 6 months. Depending on which group you're randomly assigned to, you might take the charcoal supplement (in powder form, three times daily) for 6 months, and possibly the probiotic powder (once daily) for the last 3 months. Researchers will collect blood and stool samples to study your gut bacteria, toxin levels, and blood vessel function before, during, and after treatment.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
Taiwan