Plain-English translation of NCT04804748 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is testing a new device called DefiPace that uses low-energy electrical pulses to prevent and treat an irregular heart rhythm called atrial fibrillation that sometimes happens after heart surgery. The researchers want to see if this device is safe and effective at preventing this complication in real-world hospital settings. The trial has two parts: one that looks at current standard care, and another that tests the new device in patients who receive a special temporary pacing system during surgery.
Atrial fibrillation is a common and serious complication after heart surgery that can cause problems and require additional treatment. This study exists to see whether using gentle electrical pacing can prevent this irregular heartbeat from happening in the first place, which could help patients recover better and avoid further complications.
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Depending on which part of the study you join, you will either receive standard care after your heart surgery with no special device (Phase A), or you will have a temporary electrical pacing system placed during surgery that may include the DefiPace device to help prevent irregular heartbeats (Phase B). All participants will have their hospital records collected during their stay after surgery. If you develop an irregular heartbeat or are in the group using DefiPace, you will receive a follow-up phone call 30 days after your surgery to check on your recovery.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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