Plain-English translation of NCT04807140 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called , which is a type of immunotherapy that helps your immune system fight cancer. You'll receive it before surgery for head and neck cancer. The study will compare two approaches: alone, or combined with two chemotherapy drugs.
Head and neck cancer is serious, and surgery alone doesn't always work well enough. Doctors want to see if giving immunotherapy before surgery can shrink tumors and improve outcomes. This trial will also help identify which patients benefit most from this treatment and which ones might experience side effects.
You likely qualify if…
You likely don't qualify if…
You will receive medication infusions every 3 weeks before your scheduled surgery. Depending on which group you're assigned to, you'll receive either one medication or a combination of three medications given intravenously. You'll have blood tests and imaging scans to monitor how the cancer responds, and the research team will study your immune cells to understand how the treatment works. After completing treatment, you'll have surgery as planned.
AI-generated summary from trial data · Jul 15, 2026 · Not medical advice
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