Plain-English translation of NCT04815239 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing Interpersonal and Social Rhythm Therapy (IPSRT)—a therapy approach that helps stabilize sleep patterns and daily routines—to see if it can help prevent bipolar disorder in teenagers who have a parent with bipolar disorder and are at higher risk of developing it themselves. The study will compare this therapy to a general healthy lifestyle program, delivered through video sessions over 6 months.
Up to 25% of teenagers whose parents have bipolar disorder will develop the condition themselves, often early and severely. Research shows that sleep and daily rhythm problems are an early warning sign, but there are currently no proven ways to prevent bipolar disorder in at-risk youth before symptoms appear. This study tests whether this treatment could help prevent the illness from developing in the first place.
You likely qualify if…
You likely don't qualify if…
You would start with a baseline assessment that includes psychiatric interviews and sleep evaluations, then be randomly assigned to receive either the sleep and routine therapy or a general healthy lifestyle program. Either way, you would attend 8 therapy sessions delivered over 6 months through a secure video platform. The sessions focus on understanding your bipolar risk, stabilizing your sleep and daily schedule, and strengthening your relationships—or on building a balanced lifestyle plan depending on which group you're in.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States