Plain-English translation of NCT04833465 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to find a better, more objective way to measure pain and treatment response in children and young adults with juvenile idiopathic arthritis, systemic lupus erythematosus, or fibromyalgia. Right now, doctors rely on patients' descriptions of their pain, which can be hard to compare and track. This study will measure a physiologic pain signal called a 'nociceptive index' to see if it can show how well treatments are working.
Today, treating these rheumatic conditions often involves trial-and-error—doctors try one treatment, see how it goes, then switch if needed. A more objective pain measurement could help doctors choose the right treatment faster and help patients feel better sooner.
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You'll visit the clinic for one year, with measurements taken at your regular appointments—no extra visits needed. Researchers will measure your pain response using a special test and collect information about how you're doing. Your regular treatments won't change because of the study; researchers are just observing and measuring to understand pain patterns better.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Enrollment target
~90 participants
Started
July 2021
Primary completion
April 2028
Age range
5 Years – 21 Years
Last updated on clinicaltrials.gov in July 2026.
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