Plain-English translation of NCT04839614 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing whether it's safe and feasible to perform two surgeries at the same time: removal of the uterus (to treat endometrial cancer) and weight loss surgery (to help address obesity). The study involves about 30 women at Brigham and Women's Hospital who have early-stage endometrial cancer or a pre-cancerous condition of the uterus and are living with obesity.
Obesity is the main risk factor for endometrial cancer, but when caught early, this cancer has an excellent survival rate. However, patients often struggle with weight-related health problems like heart disease, diabetes, and stroke for the rest of their lives. This study wants to see if doing weight loss surgery at the same time as cancer surgery could help patients lose weight and reduce these long-term health risks without delaying their cancer treatment.
You likely qualify if…
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If you enroll, you will be referred to the weight loss surgery center at your first cancer surgery appointment. You'll then attend a series of appointments (typically within 8-12 weeks) with a bariatric surgeon, nutritionist, and psychologist to prepare for surgery. Both your uterus removal and weight loss surgery will be performed on the same day using minimally invasive (laparoscopic) techniques. After surgery, you'll have follow-up visits with both surgical teams and support staff to monitor your recovery and help you with nutrition and lifestyle changes.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States