Plain-English translation of NCT04840264 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a combination of three chemotherapy drugs — , , and (5-FU) — for people with advanced stomach cancer that has spread to the lining of the abdomen and is causing a blockage in the bowel. The goal is to see if this medication combination can safely relieve the bowel blockage and help people feel better. The trial is divided into three groups depending on what treatments you've already received.
When advanced stomach cancer spreads to the abdominal lining, it can cause a dangerous bowel blockage that cannot be safely treated with surgery. This trial exists to test whether this medication combination can help clear the blockage and improve quality of life for people in this difficult situation.
You likely qualify if…
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You will receive chemotherapy infusions on specific days over a four-week cycle, repeated for multiple cycles. On treatment days, you'll come to the hospital or clinic to receive the three drugs through an IV — (about 1 hour), (about 3 hours), and (continuous over 24 hours). The exact schedule depends on which treatment group you're in based on your prior chemotherapy history. You will be monitored throughout treatment with blood tests and imaging to check how well the treatment is working and to manage any side effects.
AI-generated summary from trial data · Jul 17, 2026 · Not medical advice
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