Plain-English translation of NCT04842162 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , a fluorescent dye that glows under special light, can help surgeons see and remove any tiny bits of cancer that might be left behind during head and neck cancer surgery. The study uses near-infrared imaging — a type of camera that detects this glow — to check the surgical area in real time while you're in the operating room. The goal is to make sure surgeons catch every bit of cancer and leave healthy tissue behind.
Even when surgeons think they've removed all the visible cancer, sometimes microscopic cancer cells are left behind, which can lead to cancer returning. This trial is testing whether this medication and imaging technique could help surgeons be more thorough and improve outcomes for patients with head and neck cancer.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would undergo your planned head and neck cancer surgery at the hospital. During the surgery, surgeons would inject the special dye () and use near-infrared imaging to examine the surgical area and make sure all the cancer has been removed. You would have follow-up visits to track your recovery and health after surgery. The study involves about 65 patients total across the participating hospital.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Belgium
France
Phase
Testing effectiveness
Sponsor
Gustave Roussy, Cancer Campus, Grand Paris
Enrollment target
~65 participants
Started
December 2020
Primary completion
November 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Philippe Gorphe, MD
Gustave Roussy, Cancer Campus, Grand Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.