Plain-English translation of NCT04844606 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This is a long-term study testing a medication called in children and adolescents who have ulcerative colitis or Crohn's disease—both types of inflammatory bowel disease. The study will follow participants for about 3.5 years to see how well the medication works over time and whether it is safe to use. Participants will receive the medication as an injection under the skin, with doses tailored to their weight.
Inflammatory bowel disease in children can be serious and difficult to treat. This trial exists to understand whether this medication can help children and teens manage their condition over the long term and maintain their improvement with ongoing treatment.
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You will receive injections of the medication under your skin on a regular schedule—the exact timing and dose depend on your weight and whether you have ulcerative colitis or Crohn's disease. Over nearly 3.5 years, you will have about 44 visits to the clinic for check-ups, tests, and follow-up assessments. If your symptoms start to return, you may receive a different form of the medication given through an IV. After the main study ends, you may have the chance to continue receiving the medication through an extended access program.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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