Plain-English translation of NCT04844606 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This is a long-term study testing , a new injectable medication designed to help children and teenagers whose ulcerative colitis or Crohn's disease hasn't been adequately controlled with other treatments. The medication works by targeting a specific part of the immune system that drives bowel inflammation. This study will follow participants for about three and a half years to see how well the treatment works and how safe it is over time.
Ulcerative colitis and Crohn's disease can be serious and difficult to manage in young people, and many patients don't respond well enough to existing treatments. This trial exists to see whether this medication can help more children and teens gain better, lasting control of their symptoms and reduce the burden of these diseases on their lives.
You likely qualify if…
You likely don't qualify if…
You would receive injections of the medication under your skin at regular intervals, with doses adjusted based on your weight. Over the course of about 172 weeks (roughly 3.5 years), you would attend approximately 44 clinic visits for check-ups, blood tests, and assessments of how well the medication is working. If your symptoms return, you may receive an additional dose given through an IV. The study also offers the option to continue receiving the medication after the main study ends if it's helping you.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States