Plain-English translation of NCT04845828 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a newer method called sentinel lymph node mapping using a special dye to help surgeons find and check only the lymph nodes most likely to contain cancer during endometrial cancer surgery. The new method is compared to the standard approach, which removes more lymph nodes. Both approaches help doctors understand your cancer stage and plan any additional treatment you might need.
Removing many lymph nodes during surgery can cause problems like swelling, bleeding, and nerve damage, without actually improving survival for patients with early-stage endometrial cancer. This trial exists to see if a gentler approach that checks fewer lymph nodes works just as well while causing fewer side effects.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will undergo surgery to remove your uterus and have your lymph nodes checked. You will be randomly assigned to either the newer sentinel lymph node mapping method or the standard lymph node removal approach. Both procedures happen during your surgery, so there are no separate hospital visits beyond your normal cancer surgery. Your doctors will follow up with you to monitor your health and recovery, and to see if either approach leads to better outcomes with fewer side effects.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
South Korea
Sponsor
Asan Medical Center
Enrollment target
~810 participants
Started
January 2022
Primary completion
December 2027
Age range
20 Years – 80 Years
Sex
Female only
Last updated on clinicaltrials.gov in February 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jeong-Yeol Park, M.D Ph.D.,
Asan Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.