Plain-English translation of NCT04848870 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Sjögren's syndrome is an autoimmune disease that damages the salivary glands, leaving the mouth very dry. This study looks at how dry mouth affects teeth and gums in Sjögren's patients, and collects saliva samples to understand what changes in saliva might increase the risk of tooth decay, wear, and gum disease.
While dry mouth is known to cause dental problems, there is not enough research documenting exactly how often tooth wear and gum disease occur in Sjögren's patients or what saliva changes are responsible. This study aims to fill that gap so doctors can better understand and prevent these complications.
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You will attend visits at the oral medicine department of Charles Foix Hospital in Paris as part of your routine Sjögren's care. During these visits, doctors will examine your teeth and gums, and you will provide saliva samples. The study will follow you for up to 5 years, with visits matching your normal dental care schedule. Your saliva samples will be stored in a research collection for future studies about dental and gum disease in Sjögren's patients.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
France
Enrollment target
~100 participants
Started
January 2022
Primary completion
January 2032
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Marjolaine GOSSET, PU-PH
Assistance Publique - Hôpitaux de Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.